Slide 1 Slide 2

Publications

2025
Short-term 24h dietary recalls from observational studies cannot support claims on mortality.
Manoogian ENC, Peterson CM, Sears DD, Playdon M, Banks S, Bonham M, Chaix A, Chow LS, Coletta A, De Cabo R, Desplats P, Dibner C, Gabel K, Johnson SL, Kriegsfeld LJ, Hardikar S, Hawley JA, Heilbronn LK, Hogenesch J, James DL, Kleckner AS, Laferrère B, Marinac C, Panda S, Parr E, Pendergast JS, Quist JS, Ravussin E, Scheer FAJL, Swiatkiewicz I, Takahashi JS, Taub PR, Termannsen AD, Varady KA, Wilkinson MJ, Zee PC, Collet TH.
Absence of testes at puberty impacts functional development of nigrostriatal but not mesoaccumbal dopamine terminals in a wild-derived mouse.
Mun J, Jackson S, Prounis G, Phumsatitpong C, Motahari N, Kriegsfeld L, Landry M, Wilbrecht L.
2024
A pre-post trial to examine biological mechanisms of the effects of time-restricted eating on symptoms and quality of life in bipolar disorder.
Johnson SL, Murray G, Manoogian ENC, Mason L, Allen JD, Berk M, Panda S, Rajgopal NA, Gibson JC, Bower CD, Berle EF, Joyner K, Villanueva R, Michalak EE, Kriegsfeld LJ.
A randomized controlled trial to compare the effects of time-restricted eating versus Mediterranean diet on symptoms and quality of life in bipolar disorder.
Johnson SL, Murray G, Kriegsfeld LJ, Manoogian ENC, Mason L, Allen JD, Berk M, Panda S, Rajgopal NA, Gibson JC, Joyner KJ, Villanueva R, Michalak EE.
The Negative Effects of Travel on Student Athletes Through Sleep and Circadian Disruption.
Heller HC, Herzog E, Brager A, Poe G, Allada R, Scheer F, Carskadon M, de la Iglesia HO, Jang R, Montero A, Wright K, Mouraine P, Walker MP, Goel N, Hogenesch J, Van Gelder RN, Kriegsfeld L, Mah C, Colwell C, Zeitzer J, Grandner M, Jackson CL, Roxanne Prichard J, Kay SA, Paul K.
2023
Neural substrates underlying rhythmic coupling of female reproductive and thermoregulatory circuits.
Grant AD, Kriegsfeld LJ.
S-Cone Photoreceptors Regulate Daily Rhythms and Light-Induced Arousal/Wakefulness in Diurnal Grass Rats (Arvicanthis niloticus).
Kim AB, Beaver EM, Collins SG, Kriegsfeld LJ, Lockley SW, Wong KY, Yan L.
Continuous body temperature as a window into adolescent development.
Grant AD, Kriegsfeld LJ.
2022
Circadian Regulation of Hormonal Timing and the Pathophysiology of Circadian Dysregulation.
Moeller JS, Bever SR, Finn SL, Phumsatitpong C, Browne MF, Kriegsfeld LJ.
Female mice exhibit less overall variance, with a higher proportion of structured variance, than males at multiple timescales of continuous body temperature and locomotive activity records.
Smarr B, Kriegsfeld LJ.
Impact of Chronic Prenatal Stress on Maternal Neuroendocrine Function and Embryo and Placenta Development During Early-to-Mid-Pregnancy in Mice.
Gotlieb N, Wilsterman K, Finn SL, Browne MF, Bever SR, Iwakoshi-Ukena E, Ukena K, Bentley GE, Kriegsfeld LJ.
Sex Differences in Pubertal Circadian and Ultradian Rhythmic Development Under Semi-naturalistic Conditions.
Grant AD, Wilbrecht L, Kriegsfeld LJ.
Hypothalamic Overexpression of Neurosecretory Protein GL Leads to Obesity in Male C57BL/6J Mice.
Narimatsu Y, Iwakoshi-Ukena E, Fukumura K, Shikano K, Furumitsu M, Morishita M, Bentley GE, Kriegsfeld LJ, Ukena K.
Multi-Timescale Rhythmicity of Blood Glucose and Insulin Delivery Reveals Key Advantages of Hybrid Closed Loop Therapy.
Grant AD, Lewis DM, Kriegsfeld LJ.
2021
Adolescent Development of Biological Rhythms in Female Rats: Estradiol Dependence and Effects of Combined Contraceptives.
Grant AD, Wilbrecht L, Kriegsfeld LJ.
Maternal stress during pregnancy alters fetal cortico-cerebellar connectivity in utero and increases child sleep problems after birth.
van den Heuvel MI, Hect JL, Smarr BL, Qawasmeh T, Kriegsfeld LJ, Barcelona J, Hijazi KE, Thomason ME.
2020
Ultradian rhythms in heart rate variability and distal body temperature anticipate onset of the luteinizing hormone surge.
Grant AD, Newman M, Kriegsfeld LJ.
The Impact of Di-2-Ethylhexyl Phthalate on Sperm Fertility.
Khasin LG, Della Rosa J, Petersen N, Moeller J, Kriegsfeld LJ, Lishko PV.
Neurosecretory protein GL induces fat accumulation in mice.
Shikano K, Iwakoshi-Ukena E, Saito T, Narimatsu Y, Kadota A, Furumitsu M, Bentley GE, Kriegsfeld LJ, Ukena K.
2019
Time-of-day-dependent sensitivity of the reproductive axis to RFamide-related peptide-3 inhibition in female Syrian hamsters.
Gotlieb N, Baker CN, Moeller J, Kriegsfeld LJ.
Circadian dysfunction in the Q175 model of Huntington's disease: Network analysis.
Smarr B, Cutler T, Loh DH, Kudo T, Kuljis D, Kriegsfeld L, Ghiani CA, Colwell CS.
Neurosecretory Protein GL Induces Fat Accumulation in Chicks.
Shikano K, Iwakoshi-Ukena E, Kato M, Furumitsu M, Bentley GE, Kriegsfeld LJ, Ukena K.
Functional Implications of RFRP-3 in the Central Control of Daily and Seasonal Rhythms in Reproduction.
Angelopoulou E, Quignon C, Kriegsfeld LJ, Simonneaux V.
2018
Circadian Control of Neuroendocrine Function: Implications for Health and Disease.
Gotlieb N, Moeller J, Kriegsfeld LJ.
Evidence for a Coupled Oscillator Model of Endocrine Ultradian Rhythms.
Grant AD, Wilsterman K, Smarr BL, Kriegsfeld LJ.
Pregnancy stage determines the effect of chronic stress on ovarian progesterone synthesis.
Wilsterman K, Gotlieb N, Kriegsfeld LJ, Bentley GE.
Localization and function of neurosecretory protein GM, a novel small secretory protein, in the chicken hypothalamus.
Shikano K, Bessho Y, Kato M, Iwakoshi-Ukena E, Taniuchi S, Furumitsu M, Tachibana T, Bentley GE, Kriegsfeld LJ, Ukena K.
Artifact Rejection Methodology Enables Continuous, Noninvasive Measurement of Gastric Myoelectric Activity in Ambulatory Subjects.
Gharibans AA, Smarr BL, Kunkel DC, Kriegsfeld LJ, Mousa HM, Coleman TP.
Editorial: The Roles of GnIH in Reproductive Function and Behavior.
Ubuka T, Parhar I, Kriegsfeld LJ, Tsutsui K.
Chronic subcutaneous infusion of neurosecretory protein GM increases body mass gain in chicks.
Shikano K, Taniuchi S, Iwakoshi-Ukena E, Furumitsu M, Bentley GE, Kriegsfeld LJ, Ukena K.
Effects of chronic intracerebroventricular infusion of neurosecretory protein GL on body mass and food and water intake in chicks.
Shikano K, Kato M, Iwakoshi-Ukena E, Furumitsu M, Matsuura D, Masuda K, Tachibana T, Bentley GE, Kriegsfeld LJ, Ukena K.
2017
Food restriction-induced changes in motivation differ with stages of the estrous cycle and are closely linked to RFamide-related peptide-3 but not kisspeptin in Syrian hamsters.
Benton NA, Russo KA, Brozek JM, Andrews RJ, Kim VJ, Kriegsfeld LJ, Schneider JE.
Neural Versus Gonadal GnIH: Are they Independent Systems? A Mini-Review.
George E Bentley, Kathryn Wilsterman, Darcy K Ernst, Sharon E Lynn, Molly J Dickens, Rebecca M Calisi, Lance J Kriegsfeld, Daniela Kaufer, Anna C Geraghty, Dax viviD, Nicolette L McGuire, Patricia C Lopes, Kazuyoshi Tsutsui.
The Preoptic Area and the RFamide-Related Peptide Neuronal System Gate Seasonal Changes in Chemosensory Processing.
Jennings KJ, Chasles M, Cho H, Mikkelsen J, Bentley G, Keller M, Kriegsfeld LJ.
RFamide-related Peptide-3 and the Trade-off between Reproductive and Ingestive Behavior.
Schneider JE, Benton NA, Russo KA, Klingerman CM, Williams WP 3rd, Simberlund J, Abdulhay A, Brozek JM, Kriegsfeld LJ.
Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity.
Iwakoshi-Ukena E, Shikano K, Kondo K, Taniuchi S, Furumitsu M, Ochi Y, Sasaki T, Okamoto S, Bentley GE, Kriegsfeld LJ, Minokoshi Y, Ukena K.
Maternal and Early-Life Circadian Disruption Have Long-Lasting Negative Consequences on Offspring Development and Adult Behavior in Mice.
Smarr BL, Grant AD, Perez L, Zucker I, Kriegsfeld LJ.
Neurosecretory Protein GL, a Hypothalamic Small Secretory Protein, Participates in Energy Homeostasis in Male Mice.
Matsuura D, Shikano K, Saito T, Iwakoshi-Ukena E, Furumitsu M, Ochi Y, Sato M, Bentley GE, Kriegsfeld LJ, Ukena K.
Sex differences in variability across timescales in BALB/c mice.
Smarr BL, Grant AD, Zucker I, Prendergast BJ, Kriegsfeld LJ.
2016
Risky decision-making in adolescent girls: The role of pubertal hormones and reward circuitry.
Op de Macks ZA, Bunge SA, Bell ON, Wilbrecht L, Kriegsfeld LJ, Kayser AS, Dahl RE.
A System for In Vivo Imaging of Hepatic Free Fatty Acid Uptake.
Park HM, Russo KA, Karateev G, Park M, Dubikovskaya E, Kriegsfeld LJ, Stahl A.
The Pathophysiologic Role of Disrupted Circadian and Neuroendocrine Rhythms in Breast Carcinogenesis.
Ball LJ, Palesh O, Kriegsfeld LJ.
Detection of Successful and Unsuccessful Pregnancies in Mice within Hours of Pairing through Frequency Analysis of High Temporal Resolution Core Body Temperature Data.
Smarr BL, Zucker I, Kriegsfeld LJ.
The Role of RFamide-Related Peptide-3 in Age-Related Reproductive Decline in Female Rats.
Geraghty AC, Muroy SE, Kriegsfeld LJ, Bentley GE, Kaufer D.
Aggressive interactions are associated with reductions in RFamide-related peptide, but not kisspeptin, neuronal activation in mice.
Jennings KJ, Chang J, Cho H, Piekarski DJ, Russo KA, Kriegsfeld LJ.
2015
Contribution of GnIH Research to the Progress of Reproductive Neuroendocrinology.
Tsutsui K, Ubuka T, Son YL, Bentley GE, Kriegsfeld LJ.
Circadian Control of the Female Reproductive Axis Through Gated Responsiveness of the RFRP-3 System to VIP Signaling.
Russo KA, La JL, Stephens SB, Poling MC, Padgaonkar NA, Jennings KJ, Piekarski DJ, Kauffman AS, Kriegsfeld LJ.
Knockdown of hypothalamic RFRP3 prevents chronic stress-induced infertility and embryo resorption.
Geraghty AC, Muroy SE, Zhao S, Bentley GE, Kriegsfeld LJ, Kaufer D.
Dorsomedial hypothalamic lesions counteract decreases in locomotor activity in male Syrian hamsters transferred from long to short day lengths.
Jarjisian SG, Butler MP, Paul MJ, Place NJ, Prendergast BJ, Kriegsfeld LJ, Zucker I.
Seasonal control of gonadotropin-inhibitory hormone (GnIH) in birds and mammals.
Kriegsfeld LJ, Ubuka T, Bentley GE, Tsutsui K.
2014
Effects of Pinealectomy and Short Day Lengths on Reproduction and Neuronal RFRP-3, Kisspeptin, and GnRH in Female Turkish Hamsters.
Piekarski DJ, Jarjisian SG, Perez L, Ahmad H, Dhawan N, Zucker I, Kriegsfeld LJ.
Circadian rhythms have broad implications for understanding brain and behavior.
Silver R, Kriegsfeld LJ.
A time to remember: the role of circadian clocks in learning and memory.
Smarr BL, Jennings KJ, Driscoll JR, Kriegsfeld LJ.
Central and direct regulation of testicular activity by gonadotropin-inhibitory hormone and its receptor.
Ubuka T, Son YL, Tobari Y, Narihiro M, Bentley GE, Kriegsfeld LJ, Tsutsui K.
2013
Effects of social environment on baseline glucocorticoid levels in a communally breeding rodent.
Woodruff JA, Lacey EA, Bentley GE, Kriegsfeld LJ.
Animal Care Practices in Experiments on Biological Rhythms and Sleep: Report of the Joint Task Force of the Society for Research on Biological Rhythms and the Sleep Research Society.
Bittman EL, Kilduff TS, Kriegsfeld LJ, Szymusiak R, Toth LA, Turek FW; Joint Task Force of the Society for Research on Biological Rhythms and the Sleep Research Society.
Gonadotropin-Inhibitory Hormone Reduces Sexual Motivation But Not Lordosis Behavior In Female Syrian Hamsters (Mesocricetus auratus).
Piekarski DJ, Zhao S, Jennings KJ, Iwasa T, Legan SJ, Mikkelsen JD, Tsutsui K, Kriegsfeld LJ.
Dorsomedial hypothalamic lesions block Syrian hamster testicular regression in short day lengths without diminishing increased testosterone negative-feedback sensitivity.
Jarjisian SG, Piekarski DJ, Place NJ, Driscoll JR, Paxton EG, Kriegsfeld LJ, Zucker I.
Review: regulatory mechanisms of gonadotropin-inhibitory hormone (GnIH) synthesis and release in photoperiodic animals.
Tsutsui K, Ubuka T, Bentley GE, Kriegsfeld LJ.
Circadian regulation of kisspeptin in female reproductive functioning.
Kriegsfeld LJ.
2012
Circadian control of neuroendocrine circuits regulating female reproductive function.
Williams WP 3rd, Kriegsfeld LJ.
Gonadotropin-inhibitory hormone (GnIH): discovery, progress and prospect.
Tsutsui K, Ubuka T, Bentley GE, Kriegsfeld LJ.
Identification, expression, and physiological functions of Siberian hamster gonadotropin-inhibitory hormone.
Ubuka T, Inoue K, Fukuda Y, Mizuno T, Ukena K, Kriegsfeld LJ, Tsutsui K.
2011
Maternal programming of sexual attractivity in female Long Evans rats.
Sakhai SA, Kriegsfeld LJ, Francis DD.
Food Restriction-Induced Changes in Gonadotropin-Inhibiting Hormone Cells are Associated with Changes in Sexual Motivation and Food Hoarding, but not Sexual Performance and Food Intake.
Klingerman CM, Williams WP 3rd, Simberlund J, Brahme N, Prasad A, Schneider JE, Kriegsfeld LJ.
Circadian control of kisspeptin and a gated GnRH response mediate the preovulatory luteinizing hormone surge.
Williams WP 3rd, Jarjisian SG, Mikkelsen JD, Kriegsfeld LJ.
2010
Experimental 'jet lag' inhibits adult neurogenesis and produces long-term cognitive deficits in female hamsters.
Gibson EM, Wang C, Tjho S, Khattar N, Kriegsfeld LJ.
Recent studies of gonadotropin-inhibitory hormone (GnIH) in the mammalian hypothalamus, pituitary and gonads.
Bentley GE, Tsutsui K, Kriegsfeld LJ.
Photoperiod and Reproductive Condition Are Associated with Changes in RFamide-Related Peptide (RFRP) Expression in Syrian Hamsters (Mesocricetus auratus).
Mason AO, Duffy S, Zhao S, Ubuka T, Bentley GE, Tsutsui K, Silver R, Kriegsfeld LJ.
Overcoming sexual inhibition: exploring the role of RFamide-related peptide using a novel receptor antagonist.
Kriegsfeld LJ.
Gonadotropin-inhibitory hormone (GnIH) and its control of central and peripheral reproductive function.
Tsutsui K, Bentley GE, Bedecarrats G, Osugi T, Ubuka T, Kriegsfeld LJ.
RFamide-related peptide and messenger ribonucleic acid expression in mammalian testis: association with the spermatogenic cycle.
Zhao S, Zhu E, Yang C, Bentley GE, Tsutsui K, Kriegsfeld LJ.
2009
Proximate mechanisms driving circadian control of neuroendocrine function: Lessons from the young and old.
Williams WP 3rd, Gibson EM, Wang C, Tjho S, Khattar N, Bentley GE, Tsutsui K, Kriegsfeld LJ.
Daily changes in GT1-7 cell sensitivity to GnRH secretagogues that trigger ovulation.
Zhao S, Kriegsfeld LJ.
Aging in the circadian system: considerations for health, disease prevention and longevity.
Gibson EM, Williams WP 3rd, Kriegsfeld LJ.
2008
Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain: a novel medium for seasonal breeding in the sheep.
Smith, J. T., Coolen, L. M., Kriegsfeld, L. J., Sari, I. P., Jaafarzadehshirazi, M. R., Maltby, M., Bateman, K., Goodman, R. L., Tilbrook, A. J., Ubuka, T., Bentley, G. E., Clarke, I. J., & Lehman, M. N.
Targeted mutation of the calbindin D28K gene disrupts circadian rhythmicity and entrainment.
Kriegsfeld LJ, Mei DF, Yan L, Witkovsky P, Lesauter J, Hamada T, Silver R.
Aging in the circadian system: considerations for health, disease prevention and longevity.
Gibson EM, Williams WP 3rd, Kriegsfeld LJ.
Alterations in RFamide-related peptide expression are coordinated with the preovulatory luteinizing hormone surge.
Gibson EM, Humber SA, Jain S, Williams WP 3rd, Zhao S, Bentley GE, Tsutsui K, Kriegsfeld LJ.
Recent advances in reproductive neuroendocrinology: a role for RFamide peptides in seasonal reproduction?
Greives TJ, Kriegsfeld LJ, Bentley GE, Tsutsui K, Demas GE.
Exogenous kisspeptin does not alter photoperiod-induced gonadal regression in Siberian hamsters.
Greives TJ, Kriegsfeld LJ, Demas GE.
Circadian rhythms of photorefractory siberian hamsters remain responsive to melatonin.
Butler MP, Paul MJ, Turner KW, Park JH, Driscoll JR, Kriegsfeld LJ, Zucker I.
Monosodium glutamate-induced arcuate nucleus damage affects both natural torpor and 2DG-induced torpor-like hypothermia in Siberian hamsters.
Pelz KM, Routman D, Driscoll JR, Kriegsfeld LJ, Dark J.
2007
Suppression of kisspeptin expression and gonadotropic axis sensitivity following exposure to inhibitory day lengths in female Siberian hamsters.
Mason, A. O., Greives, T. J., Scotti, M. A., Levine, J., Frommeyer, S., Ketterson, E. D., Demas, G. E., & Kriegsfeld, L. J.
Environmental control of kisspeptin: implications for seasonal reproduction.
Greives TJ, Mason AO, Scotti MA, Levine J, Ketterson ED, Kriegsfeld LJ, Demas GE.
2006
Interactions of gonadotropin-releasing hormone (GnRH) and gonadotropin-inhibitory hormone (GnIH) in birds and mammals.
Bentley GE, Kriegsfeld LJ, Osugi T, Ukena K, O'Brien S, Perfito N, Moore IT, Tsutsui K, Wingfield JC.
Driving reproduction: RFamide peptides behind the wheel.
Kriegsfeld LJ.
The regulation of neuroendocrine function: Timing is everything.
Kriegsfeld LJ, Silver R.
Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals.
Kriegsfeld LJ, Mei DF, Bentley GE, Ubuka T, Mason AO, Inoue K, Ukena K, Tsutsui K, Silver R.
2005
Two antiphase oscillations occur in each suprachiasmatic nucleus of behaviorally split hamsters.
Yan L, Foley NC, Bobula JM, Kriegsfeld LJ, Silver R.
Signaling within the master clock of the brain: localized activation of mitogen-activated protein kinase by gastrin-releasing peptide.
Antle MC, Kriegsfeld LJ, Silver R.